Aia ka mea kanu cannabis ma luna o 120 phytocannabinoids a me 500+ terpenes i loaʻa nā hopena āpau, ʻaʻole wale ma ke kino, akā ma luna o kekahi. ʻO kēia hopena synergistic i loaʻa iā lākou kekahi i kekahi i kapa ʻia ʻo ka hopena entourage.
Me ka nui o ka hoʻohana ʻana i ka CBD no lākou iho a hāʻawi pū i kā lākou ʻīlio, nā pōpoki, a me nā holoholona ʻē aʻe no ke kōkua me nā mea āpau mai hoʻēmi i ka hopohopo i ke kākoʻo ʻana i ke olakino holoʻokoʻa, pono ke aʻo ʻana e pili ana i ka ins a me waho o ka hopena entourage. Ma ka hana ʻana pēlā, hiki iā ʻoe ke hana i nā huahana CBD i ʻoi aku ka maikaʻi no ʻoe a me kāu mau holoholona.
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Pehea e hana like ai ka Cannabis Cannabinoids a me Terpenes
No ka hoʻomaopopo ʻana pehea e hana like ai nā cannabinoids a me nā terpenes e hana i ka hopena entourage, pono mākou e nānā i kahi ʻōnaehana hoʻoponopono i kapa ʻia ʻo ka endocannabinoid system (ECS).
Hoʻokumu ʻia me nā mea hoʻopaʻa kelepona a me nā neurotransmitters e kuhikuhi ana iā lākou, e haʻi ana i ke kelepona i ka hana kaulike e hoʻokō ai, he mea nui ka ECS i ke olakino a me ke ola. No ka laʻana, hiki i ka ECS ke kōkua i ka hoʻomaha ʻana i ka ʻāʻī i ka wā i hoʻonui ʻia ai ka ʻōnaehana pale a hoʻopuka i nā mea ʻona he nui.
ʻO kekahi o nā ʻōnaehana ECS he kuleana koʻikoʻi i ke kākoʻo ʻana:
- ʻO ke aʻo ʻana a me ka hoʻomanaʻo
- Hoʻoponopono manaʻo
- hiamoe
- ʻO ke kaohi o ka pale
- Hoʻomalu ʻeha
- ʻO nā pane ʻeha a me ka immune
- ʻO ka ʻai a me ka ʻai
Hiki i nā Cannabinoids a me nā terpenes ke hoʻololi i nā hopena o kēlā me kēia ma ka ECS a me nā mea hoʻokipa koʻikoʻi ʻē aʻe, e like me ka serotonin receptors, ma nā ʻano he nui.
ʻO ka hopena Entourage: Laʻana 1
ʻO kekahi o nā ala nui e hoʻopili ai nā phytocompounds i kekahi i kekahi ma o ka hoʻopaʻa ʻana i nā mea hoʻokipa ma mua o ka hiki ʻana o kekahi pūhui. Hiki i kēia ke pale i ka cannabinoid a i ʻole terpene holoʻokoʻa, e ʻae iā ia e hele i ka ʻimi ʻana i nā mea loaʻa ʻole. Eia kekahi, hiki iā lākou ke hana i kahi poloka ʻāpana, pale i kahi phytocompound ʻē aʻe mai ka hoʻopaʻa piha ʻana i ka mea loaʻa.
Eia kekahi, ʻo nā cannabinoids a me nā terpenes nā agonists a me nā antagonist ma nā ʻokoʻa like ʻole. Hiki i ka agonist ke ho'āla i nā mea loaʻa a hiki ke kāohi i nā pūhui ʻē aʻe mai ka hoʻopaʻa ʻana ma muli o lākou ma o ka lawe ʻana i nā wahi paʻa.
ʻO kahi antagonist ke hele i mua, akā naʻe. ʻAʻole hiki iā ia ke lawe i kahi wahi paʻa mai kahi cannabinoid ʻē aʻe, akā hiki iā ia ke pale aku i ka ʻae ʻana mai ka hoʻāla ʻana ʻoiai inā loaʻa nā wahi paʻa.
ʻO ka hopena Entourage: Laʻana 2
Ua ʻike ʻia nā mea hoʻohui i ka cannabis, ʻo ia hoʻi nā terpenes, e hoʻoikaika i ka pale koko-lolo ma o ka hōʻemi ʻana i ke kūʻē a me ka hoʻihoʻi ʻana i ka permeability. Kōkua kēia i nā cannabinoids e like me cannabidiol (CBD) e maʻalahi maʻalahi, e hopena i nā dosages haʻahaʻa a me ka nui a me ka ikaika o nā hopena.
No ka laʻana, ʻaʻole pono nā cannabinoids e hele i ka pale koko-lolo e wehe i kā lākou mau mea analgesic, akā hana nui lākou inā makemake mākou i kā lākou hopena antinociceptive ma luna. ʻO nā antinociceptives nā mea e pale ai eha nā hōʻailona ma nā pae like ʻole ma ke ala ʻeha, ʻoiai nā analgesics e hoʻololi i ka ʻike o ka ʻeha.
Ka Entourage Effect Controversy
ʻOiai ua loaʻa i ka noiʻi nā hōʻike o ka hui pū ʻana o ka cannabis, a 2020 hōʻike ua pale aku i ka manaʻo he mea maikaʻi mau ka hopena entourage.
Hoʻomaopopo nā mea kākau o ka loiloi he nui ka ʻokoʻa ma waena o ka noiʻi palena ʻana e pili ana i ka hopena o ka entourage e hāʻawi i nā hopena maikaʻi a me nā mea hana CBD e hoʻopaʻa piha iā ia, ʻoiai ke kūʻai aku nei i kā lākou huahana.
Ma muli o ka nui o nā mea hoʻohui, ʻike ʻia ka nui o ia mau mea i nā ʻāpana wale nō akā e ʻike ʻia ana ka mana, paʻakikī loa ka hoʻoholo ʻana i nā cannabinoids a me nā terpenes e hana maikaʻi loa a me ka ratio.
Me kēlā mau pūhui he nui, ʻo ka helu o nā hui e hiki iā mākou ke hana he hōkū, a ʻaʻole ia e noʻonoʻo i ka ʻike ʻia ʻana o nā pūhui i nā nui like ʻole (concentrations).
Eia naʻe, ʻike ʻia kēlā cannabinoid kaawale hana pinepine i nā hopena like ʻole. No ka laʻana, ʻoi aku ka maʻalahi o nā mea hoʻokaʻawale THC i ka hoʻoulu ʻana i ka paranoia, no ka mea, ʻaʻohe cannabinoids ʻē aʻe e hoʻopaʻa i ka hiki o THC ke overstimulate CB1 receptors.
ʻOiai ʻo nā mea hoʻokaʻawale i loaʻa i ka CBD pono ke kiʻekiʻe ma mua o nā dosages maʻamau a loaʻa nā hopena liʻiliʻi i hoʻohālikelike ʻia i nā huahana CBD spectrum piha.
ʻO wai ka huahana CBD ka hopena Entourage maikaʻi loa?
Ke ʻimi nei i ka hopena entourage piha loa, ʻoi aku ka maikaʻi o nā huahana CBD spectrum piha, no ka mea aia lākou i nā cannabinoids a me nā terpenes i hāʻawi ʻia e ka mea kanu cannabis.
Hoʻolaha i kahi hopena Entourage maikaʻi
ʻOiai mākou i aʻo ai he mea maoli ka hopena entourage, ua aʻo pū mākou ʻaʻole pono mākou e hoʻohālikelike me nā pōmaikaʻi maikaʻi.
Eia nō naʻe, me kahi hoʻokolohua liʻiliʻi, hiki iā ʻoe ke hele lōʻihi i ka hōʻoia ʻana e hāʻawi mau ana i kāna mea maikaʻi loa. A hiki iā ʻoe ke hana i ka hui ʻana a me ka hoʻohālikelike ʻana i nā huahana cannabis.
Inā ʻaʻole ʻoe a i ʻole kāu holoholona i ʻike i ka THC - ʻaʻole nui - ʻo CBD spectrum piha ka huahana CBD maikaʻi loa e hoʻomaka me. A ʻoiai ma hope, hāʻawi mau ia i kahi kumu nui.
I ka hiki ʻana i ke kanaka, ʻo ka hana kūpono aʻe e hoʻohui i kahi mea hoʻokaʻawale THC a i ʻole kahi huahana THC kikoʻī piha i loko o ka hui. No ka mea ʻoiai ʻo THC wale nō ke kuleana no ka hāʻawi ʻana i nā mea kanu mariuana i ko lākou hiki ke hoʻoulu i kahi kiʻekiʻe, he therapeutic loa ia.
ʻO nā cannabinoids, ʻo ia hoʻi, ʻo CBD, hana maikaʻi e pale iā THC mai ka hoʻoulu ʻana i nā mea hoʻokipa he nui, hoʻopau a hoʻopau paha i ka kiʻekiʻe, akā ʻo ka nui o THC āu e hoʻohui ai i kāu CBD, ʻoi aku ka nui o nā hopena e like me nā hopena o ka marijuana.
Inā makemake ʻoe e pale i kēlā kiʻekiʻe a makemake paha e hoʻomaikaʻi ʻO CBD nā hopena spectrum piha no kāu holoholona, he mea hoʻokaʻawale CBD hana maikaʻi. CBG a me Nā huahana CBN ke kaulana nei a hiki ke lilo i mea hoʻohui maikaʻi loa,
aka, e akahele. No ka mea, oiai CBG a ʻaʻole psychoactive ʻo CBN ma ke ʻano like me THC, ʻo ia hoʻi, ʻaʻole ia he kumu euphoric kiʻekiʻe, ʻoi aku ka psychoactive ma mua o CBD ma muli o ka hoʻoulu ʻana i nā mea hoʻokipa ma ka lolo.
ʻO ka mea maʻamau, ʻōlelo ka poʻe he nui ka CBG e like me ka caffeine rush a hoʻolilo iā lākou i mea ʻoi aku ka launa pū ʻana, ʻoiai ʻo CBN e hāpai i ka hoʻomaha a me ka hoʻomaha.
ʻO ke alanui nui
Ke ʻimi nei i ka hopena entourage nui loa, ʻo CBD spectrum piha ka mea e hele ai. Eia nō naʻe, ʻo ka hoʻohana ʻana i nā huahana cannabis i ka tandem he ala maikaʻi loa ia e hoʻoponopono i ka hopena entourage i kāu mau pono. No laila, mai makaʻu ʻoe i ka hoʻokolohua, e hoʻopaʻa pono ʻoe i kāu noiʻi mua.
